SCIENTIFIC PROGRAMME

Рассмотрение тезисов
  1. Научный комитет рассмотрит все представленные материалы и примет решения о включении тезисов в Программу Конгресса в виде устного или постерного доклада.
  2. После рассмотрения тезисов автор будет проинформирован о решении Научного комитета по электронной почте.
  3. Авторы будут уведомлены о решении в июле 2018 г.
Рассмотрение тезисов
  1. Научный комитет рассмотрит все представленные материалы и примет решения о включении тезисов в Программу Конгресса в виде устного или постерного доклада.
  2. После рассмотрения тезисов автор будет проинформирован о решении Научного комитета по электронной почте.
  3. Авторы будут уведомлены о решении в июле 2018 г.
Рассмотрение тезисов
  1. Научный комитет рассмотрит все представленные материалы и примет решения о включении тезисов в Программу Конгресса в виде устного или постерного доклада.
  2. После рассмотрения тезисов автор будет проинформирован о решении Научного комитета по электронной почте.
  3. Авторы будут уведомлены о решении в июле 2018 г.
of Joint International Meeting
«COITH-2018 together with 9th Russian Conference on Clinical Hemostasiology and Hemorheology»
Day 1st (October 4th, 2018; Thursday)
Day 2nd (October 5th, 2018; Friday)
Day 3rd (October 6th, 2018; Saturday)
09:30 – 11:00
BLUE 4+5


Russian-Kyrgyz Symposium on Thrombosis and Hemostasis
Different countries, common problems, joint solutions
Moderators: Mamatov S.M., Roitman E.V.

09:30 – 09:45
Development of hemostasis service in Kyrgyzstan (Mamatov S.M.)

09:45 – 10:00
Monitoring system for patients taking indirect anticoagulants (Khruslov M.V.)

10:00 – 10:15
Effectiveness of using high-altitude climatotherapy in children with idiopathic thrombocytopenic purpura (Arstanbekova M., Aizhamal E.k., Mamatov S., Makhmanurov A., Imanalieva F.)

10:15 – 10:30
Yekaterinburg city mobile hemostasis team (Brazhnikov A.Yu.)
GREEN 8


09:30 – 10:30
Extracurricular symposium with the support of Pfizer
Chairs: Vavilova T.V., Averkov O.V.

Pharmacokinetics of the drug as a basis for efficacy and safety (Vavilova T.V.)

Management of a patient with PE in a modern clinic (Averkov O.V.)

Practical aspects of long-term anticoagulant therapy in patients with venous thromboembolism: clinical analysis (Vereina N.K.)
GREEN 10


Scientific Session 2
Thrombosis and Hemostasis in Pediatrics Chairs: Svirin P.V., Zharkov P.A.

09:30 – 09:45
Comparison of functional methods for diagnosis of hemorrhagic thrombocytopathy in children (Fedorova D., Zharkov P.A., Ignatova A., Polokhov D., Poletaev A.)

09:45 – 10:00
Characteristics of immune conflicts in neonatal alloimmune thrombocytopenia in Russian population (Khaspekova S., Golovkina L., Golubeva N., Shustova O., Donyush E.)

10:00 – 10:15
Deficiency of XII clotting factor – «a lot of knowledge, a lot of sadness» (Sokolova N., Vaynyunskaya N.)

10:15 – 10:30
Clinical manifestations of antiphospholipid syndrome in children (Papayan K., Kozyreva S., Kotel'nikov P.)

10:30 – 10:45
Outlook of treatment of patients with hemophilia and inhibitor to FVIII or FIX (Svirin P., Petrov V., Vdovin V., Yatsenko E., Ageenkova A.)

10:45 – 11:00
Management of children with Henoch-Schönlein purpura using heparin. Is it safe? (Sokolova N.)
BLUE 1


Scientific Session 3 with the participation of Sechenov University
Anticoagulants and atrial fibrillation: the art of risk management
Chairs: Baranova E.I., Napalkov D.A.

09:30 – 09:50
Atrial fibrillation, anticoagulants and daily clinical practice (Novikova T.N.)

09:50 – 10:10
Diagnostic value of fibroesophagogastroduodenoscopy in patients with atrial fibrillation and indications for anticoagulant therapy (Baranova E.I., Filatova A.G., Ionin V.A., Katsap A.A., Kolesnik O.S., Petukhova D.I.)

10:10 – 10:30
Efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation and chronic kidney disease: open prospective study (Daaboul I.S., Sokolova A.A., Napalkov D.A.)

10:30 – 10:45
Antithrombotic therapy in patients with atrial fibrillation. Do doctors follow guidelines in real practice? (Fedorin M., Okhotnikova P., Skirdenko J.)

10:45 – 11:00
Laboratory predictors of unprovoked bleeding in patients receiving direct oral anticoagulants (Trofimovskaya N., Novosadov M., Gabitova M.A., Sokolova A.A., Napalkov D.A.)
GREEN 9


Scientific Session 1 with auspices of European Mediterranian League against Thrombotic Diseases
Applied platelet physiology. Platelets and its monitoring. Antiplatelet therapy in cardiovascular disorders (rus/eng; with synchr.translation)
Chairs: Padro T., Sirotkina O.V., Mazurov A.V.

09:30 – 09:45
Microparticles containing microRNAs in the platelet function (Sirotkina O.V.)

09:45 – 10:00
Complex of genetic regulation for platelet function in outpatients with peripheral artery diseases underwented reconstructive surgery (Topanova A.A., Surint N.A., Isayev L.A., Sirotkina O.V.)

10:00 – 10:15
Reference intervals determination of platelet aggregation in vitro: how it should be and how it really is (Isaeva L.A., Vavilova T.V.)

10:15 – 10:30
Platelets, vesicles and inflammation (Vasilieva E.Yu.)

10:30 – 10:45
Platelet adhesion to fibrinogen-coated surface in whole blood under flow condition (Avtaeva Yu.N., Gabbasov Z.A.)

10:45 – 11:00
Discussion
11:00 – 11:30 Coffee break «Many-faced hemostasis»
Lecterium (rus)

11:00 – 11:45
Lecture 1.
Mega-world of platelets - the evolution of knowledge (Sirotkina O.V.)

11:45 – 12:30
Lecture 2.
Epigenetic mechanisms of hemostasis system regulation (Kuznik B.I.)

12:30 – 13:15
Lecture 3.
Antiphospholipid syndrome (new aspects of pathogenesis, determination of the risk profile, tactics of managing patients depending on the clinical situation and risk profile) (Vereina N.K.).

13:15 – 14:00
Lecture 4.
Clinical phenotypes of DIC syndrome (Momot A.P.)
11:30 – 13:00 Scientific Session 4
Bleeding disorders. New insights and treatment modalities (rus/eng; with synchr.translation)
Chairs: Rodeghiero F., Mannucci P.M.

11:30 – 11:45
Management of von Willebrand disease (Rodeghiero F.)

11:45 – 12:00
The role of splenectomy in ITP: a historical perspective (Varon D.)

12:00 – 12:15
ITP: which approach to refractory cases? (Rodeghiero F.)

12:15 – 12:30
Thrombotic microangiopathies (TMA): why a differential diagnosis between TTP and HUS is warranted (Mannucci P.M.)

12:30 – 12:45
Treatment of difficult cases (Coppo P.)

12:45 – 13:00
TBA
Scientific Session 5 supported by International Society for Fibrinolysis and Proteolysis
ISFP
Fibrinolysis, Proteolysis, Microparticles (rus/eng; with synchr.translation)
Chairs: Colucci M., Momot A.P.

11:30 – 11:50
Regulatory mechanism of the fibrinolytic activity and its related disorders (Urano T., Suzuki Y., Brzoska T., Sano H.)

11:50 – 12:10
A possible role of fibrinolysis for preventing thrombosis at the end of normal pregnancy (Momot A., Kudinova I.)

12:10 – 12:30
Primary hyperfibrinolysis as a cause of bleeding: myth or reality? (Coccheri S.)

12:30 – 12:45
Microenvironmental regulation of fibrinolysis in comorbid patients with chronic cerebrovascular diseases (Roitman E., Tanashyan M., Shabalina A., Kolesnikova I.)

12:45 – 13:00
Effect of tranexamic acid on fibrinolysis in large orthopedic surgery: practice against theory? (Antropova I., Zhirova T.)
Extracurricular symposium on 70th anniversary of thromboelastography, with the support of Werfen
«Thromboelastography and thromboelastometry: 70 years together» Chairs: Bulanov A.Yu., Mazurok V.A.

11:30 – 11:45
Clinical aspects of thromboelastometry in cardiosurgery (Rybka M.M., Rogalskaya E.A., Samsonova N.N.)

11:45 – 12:00
Can thromboelastometry (ROTEM) be replaced or supplemented with a standard coagulation test? (Galstyan G.M., Polevodova O.A.)

12:00 – 12:15
The thromboelastography in express diagnosis of hemostasis disorders (Mazurok V.A., Yakubov A., Bautin A.)

12:15 – 12:30
Thromboelastometry - a method for solution support in cardioanesthesiology? (Akselrod B.A., Dymova O.V., Kolbintsev S.I., Guskov D.A., Gladysheva V.G.)

12:30 – 12:45
The advantages of thromboelastography application in infants with congenital heart disease in cardiac surgery (Leonov N.)

12:45 – 13:00
New diagnostic techniques in thromboelastography (Paulevodova O.A., Galstyan G.M., Berkovskii A.L., Sergeeva E.L.)
Scientific Session 6 with auspices of National Centre on Neurology
Национального центра неврологии Thrombosis and Hemostasis in Neurological Patients with comorbidities. (rus/eng; with synchr.translation)
Chairs: Tanashyan M.М., Vardanyan A.V.

11:30 – 11:50
Obesity, Metabolic Syndrome and Thrombosis (Padro T.)

11:50 – 12:05
Hemorheology and hemostasis in patients with cerebrovascular disease and metabolic syndrome (Tanashyan M.)

12:05 – 12:15
Hemostasis specificity in acute disorders of cerebral circulation and Ph-negative myeloproliferative diseases (Shabalina A., Tanashyan M., Kuznetsova P., Roitman E.)

12:15 – 12:25
Cancer-associated venous thromboembolic complications: a shift of priorities in treatment tactics (Vardanyan A., Dolidze D., Tokarev K., Chizh E., Petrosyan A.)

12:25 – 12:35
Step-by-step antithrombotic therapy for ischemic stroke (Maximova M.)

12:35 – 12:45
Optimization of neurometabolic therapy of cerebrovascular diseases (Tanashyan M., Lagoda O., Antonova K., Shabalina A.)

12:45 – 12:55
The choice of optimal tactics for secondary prevention of ischemic stroke in patients with type 2 diabetes: a focus on the correction of hemorheological disorders (Sсhepankevich L.A.)

12:55 – 13:00
Discussion
13:00 – 14:30 LUNCH
POSTER VIEWING

GREEN 9


Lunch Symposium 1
Diagnosis and correction of hemostasis system (rus)
Diagnosis and correction of hemostasis system in cardiac surgery (M.M.Rybka)
Answers on questions
Diagnosis and correction of the hemostasis system in oncohematology (G.M.Galstyan)
Answers on questions
Diagnosis and correction of the hemostasis system in neurosurgical patients (A.Yu.Lubnin)
Answers on questions
14:30 – 16:00 Scientific Session 7
Thrombosis and hemostasis in pediatrics (rus/eng; with synchr.translation)
Chairs: Kenet G., Zharkov P.A.

14:30 – 14:50
How to choose antihemophilic medicines in previously untreated children with severe hemophilia A (Mannucci P.M.)

14:50 – 15:10
Platelet disorders (Vilk S.)

15:10 – 15:25
Modern views on thrombolytic therapy in children (Svirin P., Koltunov I., Shederkina I., Larina L., Lavrentieva I)

15:25 – 15:45
Treatment of thrombosis in pediatric patients - with update of DOAC studies (Van Ommen C.H.)

15:45 – 16:00
Asymptomatic venous thrombosis in children. What is the difference? (Zharkov P.A.)
Scientific Session 8 supported by International Society for Fibrinolysis and Proteolysis
ISFP
Fibrinolysis, Proteolysis, Microparticles (rus/eng; with synchr.translation)
Chairs: Urano T., Mutch N., Roitman E.V.

14:30 – 14:50
Altered fibrinolysis and bleeding in congenital coagulopathies (Colucci M.)

14:50 – 15:10
Fibrinolytic proteins within the thrombus micro environment (Mutch N.)

15:10 – 15:30
Platelets and their microparticles as key players in pathophysiological responses (Varon D.)

15:30 – 15:50
Not plasmin fibrinolysis, new possibilities of thrombolytic therapy (Madonov P., Mishenina S.)

15:50 – 16:00
The effectiveness of various thrombolytic agents for the treatment of pulmonary embolism (Khorev N., Beller A., Borovikov E., Momot A., Shoikhet Ya.)
Scientific Session 9 supported by Almazov National Medical Research Centre.
Population-, Gender- and Age-related Issues of Thrombosis
Chairs: Vavilova T.V., Sirotkina O.V.

14:30 – 14:45
Gynecological and non-gynecological risk factors for thrombosis in woman's life (Zazerskaya I.E.)

14:45 – 15:00
Thrombin generation study in patients with myocardial infarction in history (Melnichnikova O., Sirotkina O., Panov A., Nazarova I., Vavilova T.)

15:00 – 15:15
Evaluation of platelet’s functional activity by flow cytometry in "frailty" patients (Ermakov A., Kukharchik G., Gaikovaya L., Sirotkina O.)

15:15 – 15:30
Gender features of pathogenesis and course of lacunar stroke (M.S.Topuzova, E.G.Klocheva, V.V.Goldobin)

15:30 – 15:45
An elderly patient in the anticoagulant therapy control office (Zubkova P.Yu., Vavilova T.V.)

15:45 – 16:00
Molecular prognostic markers in patients with cardiovascular disease after percutaneous coronary intervention (Vasilyeva E.Yu.)
Scientific Session 10 with auspices of Samara State Medical University
Thrombosis-associated conditions in comorbid patients
Chairs: Davydkin I.L., Duplyakov D.V.

14:30 – 14:50
Prothrombogenicity in patients with atrial fibrillation, risks and prognosis of survival (Zolotovskaya I., Davydkin I.)

14:50 – 15:10
The duration of anticoagulant therapy after an episode of pulmonary embolism (Duplyakov D., Cherepanova N.)

15:10 – 15:30
Risk predictors of in-hospital mortality in patients with pulmonary embolism (Mullova I., Cherepanova N., Duplyakov D., Pavlova T., Khokhlunov S.)

15:30 – 15:45
Peculiarities of prophylaxis, diagnostics and treatment of PE in multidisciplinary hospital (Parshina S., Romanova N., Povarova T., Illarionova V., Kasimov O.)

15:45 – 16:00
Hemostatic parameters and genetic polymorphisms associated with left atrial appendage thrombosis in patients with atrial fibrillation (Rubanenko A.)
«Many-faced hemostasis»
Lecterium (rus)



14:30 – 15:15
Lecture 5.

Thrombosis and hemostasis using extracorporeal life support systems (Babaev M.A.)

15:15 – 16:00
Lecture 6.

Blood transfusion: from technical regulations to rules (on the changing regulatory framework of Russia blood service, trends for blood collection and transfusion as in Russia as well as abroad) (Zhiburt E.B.)
16:00 – 16:30 Coffee break Master Class Prof F.R.Rosendaal for Young Investigators «The Bridge to the Future» (with synchr.translation)
16:30 – 18:00 Scientific Session 11
Platelets and its monitoring. Antiplatelet therapy in cardiovascular disorders (rus/eng; with synchr.translation)
Moderators: Varon D., Cattaneo M., Buryachkovskaya L.I.

16:30 – 16:45
Which one for which category (Matetzky S.)

16:45 – 17:00
Should we test their effects (Cattaneo M.)

17:00 – 17:15
New developments in anti-platelets therapy (Varon D.)

17:15 – 17:30
Antiplatelet therapy for neurologists (Tanne D.)

17:30 – 17:45
Platelet functional activity and bleeding in childhood immune thrombocytopenia (Ignatova A.A., Zharkov P.A., Suntsova E.V., Fedorova D.A., Polokhov D.M., Ponomarenko E.A., Maschan A.A., Novichkova G.A., Panteleev M.A.)

17:45 – 18:00
The dependence of platelet adhesion on endothelial cells from the endothelial glycocalyx (Melkumyants A., Buryachkovskaya L., Antonova O., Ermishkin V.)
Scientific Session 12, dedicated to the 200th anniversary of the first blood transfusion
Bleeding disorders, Bleeding and Blood Management. New insights and treatment modalities
Chairs: Zhiburt E.B., Kolesnikov V.V.

16:30 – 16:45
Prevention and treatment of hemostasis disorders in patients with severe co-traumatic injuries in terms of the ATLS protocol (Kolesnikov V.V.)

16:45 – 17:00
Patient's blood management in a multidisciplinary clinic (Zhiburt E., Shestakov E., Chemodanov I., Gubanova M., Kozhemyako O.)

17:00 – 17:15
Selective approach to hemocomponents banking based on hemostatic parameters of donor blood (Kubiddinov A., Saidov Ju., Odinaev A.)

17:15 – 17:30
Hemostasiological parameters of pathogen-reduced plasma (Bondaruk O.)

17:30 – 17:50
Autologous blood components management in the complex preparation of planned neurosurgical operations (Bauklin A.V.)

17:50 – 18:00
Succinate-based antioxidant and nanoparticles of perfluorocarbon emulsion contribute to the reduction of methemoglobin to oxyhemoglobin (Manchenko E., Kozlova E.)
Scientific Session 13 with auspices of Kirov Scientific Research Institute of Hematology and Blood Transfusion
Hemophilia and Thrombohemorrhagic syndromes
Chairs: Ignatyev S.V., Nazarova E.L.

16:30 – 16:45
Molecular and genetic risk-associated predisposition to acute atherothrombotic conditions (Nazarova E., Suhorukova J., Nazarov D., Kovtunova M., Minaeva N.)

16:45 – 17:00
Association of congenital prothrombotic factors with clinical course of hemophilia (Poponina E., Butina E., Vyaznikova O., Sergeeva L., Timofeeva M.)

17:00 – 17:15
Individual approach to anticoagulant therapy in oncohematological patients (Ignatev S., Fokina E., Lyanguzov A., Zotina E.)

17:15 – 17:30
The use of thromboelastography for the personification of transfusion therapy in patients with leukemia and severe thrombocytopenia (Lyanguzov A., Ignatiev S., Kalinina S., Sergunina O., Sherstnev Ph.)

17:30 – 17:45
Hemostasis in patients with acute promyelocytic leukemia (Nikitin E.)

17:45 – 18:00
Pathogenetic prophylaxis of thrombohemorrhagic complications in Ph-negative myeloproliferative neoplasms (Polyakov A., Noskov Ya., Tyrenko V., Petrova O.)
«Many-faced hemostasis»
Lectorium (rus)


16:30 – 17:15
Lecture 7.

Antiphospholipid syndrome: overlap with autoimmune rheumatic disorders. (Reshetnyak T.M.)
17:15 – 18:00
Lecture 8.

Elevated cardiovascular risk in rheumatic diseases. Inflammation in the pathogenesis of atherosclerosis (Arshinov A.V.)
18:00 – 18:30 Break to walk
18:30 - 19:30
BLUE 4+5


Plenary Session (joint) Testing for prothrombotic markers: the road to personalised treatment (F.R.Rosendaal) (rus/eng; with synchr.translation)
19:30 – 21:00 Get Together Party
08:30 – 09:15
BLUE 4+5


Plenary Lecture.
Sergio Coccheri. «Contradiction and uncertainty in science and medicine: how can we prevent distrust by patients and distortion by media?»
(rus/eng; with synchr.translation)
GREEN 10

«Many-faced hemostasis»
Lectorium (rus)


08:30 – 09:15
Lecture 9.

Questions of examination and quality of medical activity (Pavlova V.Yu.)

09:15 – 10:00
Lecture 10.

Thrombophilias in obstetrics. Refutation of myths (Gurieva V.M.)

10:00 – 10:45
Lecture 11.

Non-invasive methods for hemostasis and hemodynamic studying under normal and pathological conditions (Kuznik B.I.)

10:45 - 11:30
Lecture 12.

Methodology of blood coagulation tests (Momot A.P.)
09:30 – 11:00
BLUE 4+5


Scientific Session 14
Hemophilia and other factor deficiencies, new insights and treatment modalities (rus/eng; with synchr.translation)
Chairs: Kenet G., Ljung R.

09:30 – 09:50
Rare bleeding disorders. (Kenet G.)

09:50 – 10:10
Hemophilia prophylaxis in the new era (Ljung R.)

10:10 – 10:30
New antihemophilic therapies (Kenet G.)

10:30 – 10:45
Impairments of spatial thrombin generation in patients with coagulopathy recorded with Thrombodynamics-4D assay (Kuprash A., Balandina A., Shibeko A., Panteleev M.)

10:45 – 11:00
Q&A
BLUE 1


Scientific Session 15
Antithrombotic protection in practical algorithms and models. Venous Thromboembolism. Real life use of DOACs (rus/eng; with synchr.translation)
Chairs: Vereina N.К., Antropova I.P.

09:30 – 09:50
Etiology, treatment with anticoagulants and outcomes in portal venous thrombosis (Vereina N., Pirogova I., Sinitsin S.)

09:50 – 10:20
Reversal matters; comprehensive care with dabigatran and Idarucizumab (VanRyn J.)

10:20 – 10:40
Navigating the choice of oral anticoagulation therapy for atrial fibrillation in elderly patients (Novikova T.N.)

10:40 – 10:50
Thromboses, thromboembolism and clinically significant hemorrhages in patient undergoing mitral valve replacement (Markova M.)

10:50 – 11:00
Rivaroxaban influence on microcirculation parameters in patients with peripheral arterial diseases of lower extremities (Andozhskaya Yu., Novikova A., Perova M.)
GREEN 8

Scientific Session 16 with auspices of the Russian Association of anesthesiologist and with the participation of Surgical Scientific Society «FastTrack»
Coagulation Management in Critical Care Chairs: Shlyk I.V., Gubaidullin R.R., Samsonova N.N.

09:30 – 09:45
Hemostasis in patients with sepsis (Afanasyev A.A., Shlyk I.V.)

09:45 – 10:00
New treatment options for PE (Protsenko D.N.)

10:00 – 10:15
Perioperative management of patients with anemia in oncosurgery. Problems, possible solutions. (Glushchenko V.A.)

10:15 – 10:30
Thromboelastography in the diagnostics system of hemostasis (Bulanov A.Yu., Simarova I.B., Bulanova E.L., Feklistov A.Yu.)

10:30 – 10:45
Heparin-induced thrombocytopenia II type. The real danger and diagnostic algorithm in cardiac surgery (Dymova O.V.)

10:45 – 11:00
An alternative view of indications for implantation of cava filter (Khruslov M.V., Sinitsyn A.А., Ponomareva N.A.)
GREEN 9

Extracurricular symposium with the support of Alfasigma
Habitual miscarriage in patients with thrombophilia
Chair: Balan V.E.

Pathogenetic mechanisms of habitual miscarriage (Tetruashvili N.K.)

The use of LMWH in pregnant women with hemostasis disorders (Lapina I.A.)

Possibilities of using sulodexide in the pre-gravity period in patients with habitual miscarriage (Balan V.E.)

10:30 – 11:30 Extracurricular symposium with the support of Sanofi
Topical issues of therapy and prevention of venous thrombosis
Chair: Roitman E.V.

Venous thromboembolic complications: who is to blame and what to do? (Vavilova T.V.)

Personalization of antithrombotic therapy and prevention (Roitman E.V.)

The problem of thrombosis in oncology (Vorobyova N.A.)

Thrombosis in obstetrics (Vinogradova M.A.)
11:00 – 11:30 Coffee break
11:30 – 13:00 Scientific Session 17
Venous Thromboembolism (VTE). Real life use of direct oral anticoagulants (DOACs) (rus/eng; with synchr.translation)
Chair: Lubetsky A.

11:30 – 11:50
Chronic atrial fibrillation (Lev E.)

11:50 – 12:10
Reversal agents (Lubetsky A.)

12:10 – 12:30
Risk factors of thrombotic complications in women using combined hormonal contraceptives (Vereina N., Movchan T., Chulkov V.)

12:30 – 12:50
Provoked pulmonary embolism in older adults: mortality and its risk factors (Justo Dan, Aharoni Mor, Horesh Nir, Mayan Haim)

12:50 – 13:00
TBA
Scientific Session 18 with auspices of National Medical Research Center of Obstetrics, Gynecology and Perinatology n.a. acad.V.Kulakov
Women issues-1.
Oncology, pregnancy and thrombohemorrhagic problems

Chairs: Shmakov R.G., Guryeva V.M., Ozolinya L.A.

11:30 – 11:50
Cancer and pregnancy (results of international multicenter study) (Shmakov R., Polushkina E.)

11:50 – 12:10
Pregnancy outcomes in women with hematologic neoplasms (Akhmedova A.I., Polushkina E.S., Shmakov R.G.)

12:10 – 12:25
Hematological diseases and pregnancy - the main causes Near miss in obstetrics (Vinogradova M.A.)

12:25 – 12:40
Low-molecular weight heparin for prevention of severe preeclampsia – not only anticoagulant action (Guryeva V.M., Yablokova M.E., Budikina T.S., Shoybonov B.J.)

12:40 – 13:00
The role of haemostatic potential monitoring in patients diagnosed with "Thrombophilia" at the stage of pregravid correction of identified hemostasis disorders (Tyutrin I., Klimenkova V., Udut V.)
Scientific Session 19 with auspices of the Russian Research Center of Surgery n.a. acad. Boris Petrovsky
Multiple organ failure and coagulopathy (rus/eng; with synchr.translation)
Chairs: Protsenko D.N., Scarlatescu E., Sinkov S.V.

11:30 – 11:55
Coagulation management in liver transplantation (Scarlatescu E.)

11:55 – 12:10
Coagulation disorders in patients with non-resectable liver tumors during transplantation in perioperative period (Dubrovin K.V., Kozlov S.P., Nikoda V.V., Mayachkin R.B., Lyshova E.A., Filin V.A., Kim E.F.)

12:10 – 12:25
Coagulopathy in liver diseases: when is the correction needed? (Sinkov S.)

12:25 – 12:40
Analysis of hemostasis in hepatic coagulopathy (Uvarova O., Bulanov A., Antonova I., Simarova I.)

12:40 – 12:50
Ways to prevent thromboembolism of pulmonary artery with laparoscopic interventions in patients with concomitant pathology (Grintsov A., Sovpel O., Shestopalova A., Stupacenko D.)

12:50 – 13:00
Intrinsic pathway coagulation factors activity and hemostatic markers of endothelial dysfunction in patients with atherosclerotic peripheral arterial disease (Klimentova E.)
11:30 – 12:30
Extracurricular symposium with the support of Bayer
11:30 – 12:15
Lecture 13.

Adequate control over the DOAC (Papayan L.P.)

12:15 – 13:00
Lecture 14.

Thrombosis, rheological disturbances and space weather (Parshina S.S.)
13:00 – 14:30 LUNCH for participants
POSTERS VIEWING


BLUE 4+5


13:45 – 14:30
Lecture (rus)

Prevention of VTE in oncology (update of Recommendations) (Leontiev S.)
13:00 – 13:45
Lecture 15.
Traumatic coagulopathy: modern recommendations (Sinkov S.V.)

13:45 – 14:30
Lecture 16.

Dilution coagulopathy of massive blood loss: the prevention and correction possibilities (Mazurok V.A.)

14:45 – 15:30
Lecture 17.

DIC-syndrome in terms of evidence-based medicine and real clinical practice (Vorobyova N.A.)

15:30 – 16:15
Lecture 18.

Catheter-associated thrombosis (Roitman E.V.)
14:30 – 16:00 Scientific Session 20
Cancer-associated thrombosis (CAT)
(rus/eng; with synchr.translation)

Moderators: Becattini C., Patrono C.

14:30 – 14:50
Management of CAT (Becattini C.)

14:50 – 15:10
Role of platelets in cancer (Patrono C.)

15:10 – 15:35
Hemostatic biomarkers in cancer progression (Falanga A.)

15:35 – 15:50
Errors and dangers of performing and evaluating laboratory tests for hematologic risks of thrombosis: clinical cases (Vavilova T.V.)

15:50 – 16:00
Thrombogenic dominants in chronic cerebrovascular diseases patients comorbid with myeloproliferative neoplasms (Roitman E., Shabalina A., Tanashyan M., Kolesnikova I.)
Scientific Session 21 with auspices of National Medical Research Center of Obstetrics, Gynecology and Perinatology n.a. acad.V.Kulakov
Women issues-2. Thrombohemorrhagic problems in obstetrics
Chairs: Pyregov A.V., Zainullina M.S.

14:30 – 14:50
Control of coagulation in obstetric hemorrhages (Pyregov A., Korolev A., Shmakov R., Fyodorova T.)

14:50 – 15:10
Thrombophilia and placenta-mediated pregnancy complications. Is the talk about prevention appropriate? (Zainullina M.S.)

15:10 – 15:30
Modern aspects of VTE prevention in gynecology (Ozolinya L.A., Lapina I.A.)

15:30 – 15:40
The role of comorbidity and phenotypic manifestation (APС resistance) of abnormal FVL(1691)GA genotype in the system of risk factors for thrombosis during pregnancy (Nikolaeva M., Momot A.)

15:40 – 15:50
Intraoperative acute coronary syndrome in obstetrics: interventional or standard treatment algorithm. The role of hemostasis system evaluation (Pismensky S., Golubeva O., Pyregov A.)

15:50 – 16:00
The decision algorithm for obstetric embolism (on the example of a clinical case) (Kalachin K., Pyregov A.)
Young Investigator Award. Oral Communications (rus/eng; with synchr.translation)
Chairs: Kenet G., Varon D., TBA

14:30 – 14:40
Interrelation of hemostasis changes and typical autoantibodies in children with autoimmune hepatitis (Konovalova E., Lavrova A., Presnyakova M.)

14:40 – 14:50
Study of the tendency to thrombosis in patients with vascular syndrome in connective tissue dysplasia (Kopylov A., Elykomov V.)

14:50 – 15:00
Cerebral sinovenous thrombosis in children (Maslova N., Svirin P., Schederkina I., Larina L., Kazankova A.)

15:00 – 15:10
Effectiveness and safety of radiofrequency ablation in patients with atrial fibrillation and flutter (Shidlovskaia S., Gilyarov M., Bogdanova A., Gromyko G., Safonov N.)

15:10 – 15:20
Acetylsalicylic acid sensitivity in women after coronary artery bypass surgery due to stable angina (Bekmurzinova Z.)

15:20 – 15:30
State of folate metabolism in pregnant women with complicated obstetric history (Vorobyeva N., Zvezdina Yu.)
Scientific Session 22 with auspices of European Society for Clinical Hemorheology and Microcirculation
Hemorheology and microcirculation (rus/eng; with synchr.translation)
Chairs: Brun J-F., Muravyov A.V.

14:30 – 14:45
Special Guest: Prof. Mike W Rampling. Clinical hemorheology. Great history gives a hope to the future.

14:45 – 15:00
Comparative studies of the blood coagulation kinetics and thrombus formation by rheological, electrorheological and AFM methods (Antonova N., Alexandrova A., Ivanov I., Konstantinova E., Melnikova G.)

15:00 – 15:15
Mechanisms of changes in microrheological properties of red blood cells under the influence of gasotransmitters: in vitro study (Muravyov A., Tikhomirova I., Bulaeva S., Zamyshlyaev A.)

15:15 – 15:30
RBC deformability, a tightly regulated hemorheological parameter involved in homeostatic régulations? (Brun J.-F., Varlet-Marie E., Richou M., Fidani T., Raynaud de Mauverger E.)

15:30 – 15:45
Rheometry to indicate the mechanical behavior of blood clots (Windberger U., Dibiasi C., Glanz V., Lee S.H., Plewka J., Lichtenegger H.)

15:45 – 16:00
Hemorheology and hemostasis in the surgical treatment of non-myeloid tumors (Tikhomirova I., Malysheva Yu., Ryabov M., Kislov N., Petrochenko E.)
16:00 – 16:30
Coffee break
16:30 – 18:00 Scientific Session 23
Thrombosis and cancer, cancer-associated thrombosis
(rus/eng; with synchr.translation)

Chairs: Falanga A., Roitman E.V.

16:30 – 16:45
Venous ports associated thrombosis in cancer patients (Cherkashin M., Berezina N., Suprun K., Naperov E., Yablonsky P.)

16:45 – 17:00
Dynamics of indexes of a platelet hemostasis in oncological surgery of a rectum (Larichev A., Tikhomirova I., Ryabov M., Petrochenko E., Efremov K.)

17:00 – 17:15
Treatment of VTE in patients with brain tumor undergoing surgery (Katelnitskaya O., Kit O., Rostorguev E., Kuznetsova N., Katelnitskiy I.)

17:15 – 17:30
Venous thrombosis in children, adolescents and young adults with lymphomas: incidence, characteristics, risk factors, prognostic value and anticoagulant therapy (Dmitriev V., Fedorova A., Lipay N., Dmitriev E.)

17:30 – 17:40
Possibilities of application of enoxaparin sodium in prophylaxis of hemostatic and thrombotic complications in oncology (Somonova O., Elizarova A., Matveeva I.)

17:40 – 18:00
Modern views on the perioperative anemia treatment (Khalikova E.Yu.)

18:00 – 18:10
Cancer-associated venous thromboembolic complications: a shift of priorities in treatment tactics (Vardanyan A., Dolidze D., Tokarev K., Chizh E., Petrosyan A.)
Scientific Session 24 with the participation of Pirogov Russian National Research Medical University
New insights in blood coagulation biology. Hemocoagulation and autoimmune disorders
Chairs: Roumiantsev S.A., Reshetnyak T.M.

16:30 – 16:50
Functional links between immune system and hemostasis system. Own data. (Roumiantsev S.A.)

16:50 – 17:05
The importance of inflammation and platelet activation in the development of accelerated atherosclerosis in patients with systemic lupus erythematosus (Arshinov A., Levshin N., Maslova I.)

17:05 – 17:25
The influence of single nucleotide polymorphisms in cytochrome P450 CYP2C9 and vitamin K epoxide reductase complex subunit 1 VCORC1 genes on warfarin sensitivity in patients with antiphospholipid syndrome (Reshetnyak T., Kondratyeva L., Kovalenko T., Seredavkina N., Patrushev L.)

17:25 – 17:40
The influence of disease activity and therapy on hypercoagulable state in rheumatic patients (preliminary results) (Seredavkina N., Vuimo T., Starovoytova M., Lila A., Reshetnyak T.)

17:40 – 17:55
Hemostasis, adipokine, genes polymorphisms of renin-angiotensin system and target organ damage in young patients with arterial hypertension and abdominal obesity (Chulkov V.)

17:55 – 18:00
Discussion
Scientific Session 25
Studies of the hemostasis behavior Chairs: Kuznik B.I., Momot A.P.

16:30 – 16:40
Superthreshold physical load as a factor of thrombotic readiness in rats (Blazhko A.)

16:40 – 16:50
New synthetic peptide (AP9) similar to activated protein C demonstrates the neuroprotective effect at the glutamate-induced toxicity (Babkina I., Sidorova M., Gorbacheva L.)

16:50 – 17:00
Activated protein C cancels the pro-inflammatory action of thrombin on cultured astrocytes (Goncharov M., Abramov E., Gorbacheva L.)

17:00 – 17:10
New antiaggregant with combined mechanism of action (Sirotenko V.)

17:10 – 17:20
New conception of hemostatic proteases influence on inflammation, neurotoxicity and tissue regeneration (Savinkova I., Kiseleva E., Strukova S., Gorbacheva L.)

17:20 – 17:30
Development of an irreversible inhibitor of platelet function based on N-chlorotaurinе (Murina M., Buravleva K., Roshchupkin D.)

17:30 – 17:40
Hemostatic effect of fibrin-monomer on the background of heparin use under controlled liver trauma (Vdovin V., Momot A., Shakhmatov I., Tolstokorov I., Orekhov D.)

17:40 – 18:00
Relationship of the "protein of youth" gdf11 to "proteins of old-age" ccl11, gdf15, jam-a, the condition of the hemostatic and hemodynamic systems in women with essential hypertension (Stepanov A.V., Davydov S.O., Kuznik B.I., Guseva E.S., Smolyakov Yu.N.)
Scientific Session 26 with auspices of European Society for Clinical Hemorheology and Microcirculation
Hemorheology and microcirculation
Chairs: Antonova N., Tikhomirova I.А.

16:30 – 16:40
The possible role of erythrocytes in the development of ischemic stroke (Kruchinina M., Gromov A., Generalov V., Kruchinin V., Abdullaeva P.)

16:40 – 16:55
Gender and age differences in parameters of microcirculation and oxygen transport in healthy persons. Interrelation with parameters of hemorheology and lipid metabolism (Konstantinova E., Spiridonova O.)

16:55 – 17:05
The functional properties of blood cells and their mean volume in inflammatory bowel diseases in children (Levin G., Popovicheva A., Sosnina L., Fedulova E., Sheremet'ev Yu.)

17:05 – 17:15
AFM diagnostics of erythrocyte membranes nanostructure during long-term storage of donor blood (Sergunova V., Chernysh A.)

17:15 – 17:25
Skin flap autografting biostimulation effects on microcirculation in the conditions of peripheral nerve injury (Lagutina D., Ivanov A., Ulyanov V., Norkin I.)

17:25 – 17:35
Possibilities of high-frequency ultrasound dopplerography in assessment of penis microcirculation in patients with erectile disfunction (Slesarevskaya M., Al-Shukri S., Kuzmin I., Krotova N., Telegin I.)

17:35 – 17:45
State of hemostasis and microcirculation in different periods after hypothermia in rats (Lycheva N.)

17:45 – 17:55
Features of endothelial-independent and endothelial-dependent vasodilatation of the microcirculatory bed and the function of vascular endothelium in healthy variously-aged people (Khalepo O., Molotkov O., Grigorieva L., Feoktistova Z.)

17:55 – 18:00
Discussion
Master Class
P.M.Mannucci for Young Investigators «The Bridge to the Future»
(with synchr.translation)

A general approach to the many current issues on congenital and acquired bleeding disorders
08:30

09:00 – 10:30

BLUE 1


Scientific Session 27
From basic research to the clinic
Chairs: Papayan L.P., Levshin N.Yu.

09:00 – 09:20
Syndrome of elongated APTT (Papayan L.)

09:20 – 09:35
From overdiagnosis to rational clinical thrombophilia understanding (Levshin N.Yu.)

09:35 – 09:50
The possibilities of laboratory prediction of outcomes in cycles of in vitro fertilization (Safiullina S., Vuimo T., Kotova Ya., Ilizarova N.)

09:50 – 10:05
Comparative thromboelastography analysis of modern antiplatelet agents and new benzimidazole derivatives (Uskov G., Gaidukova K,)

10:05 – 10:20
The possibility of applying pharmacogenetic testing for the prevention of stent thrombosis (Barysheva V., Ketova G., Kremlev S.)

10:20 – 10:30
Discussion

GREEN 9


Scientific Session 28
Genetics hemostasis
Chairs: Vorobyeva N.A., Kapustin S.I.

09:00 – 09:15
Polymorphism of tissue plasminogen activator and PAI-1 genes and peculiarities of venous thromboembolism manifestation in young patients (Chechulova A,, Kapustin S., Soldatenkov V., Kargin V., Soroka V.)

09:15 – 09:30
Genetic factors affecting homocysteine metabolism in the Nenets population of the Nenets Autonomous Region (Vorobyeva N., Belova N.)

09:30 – 09:45
Unusually high prevalence of the prothrombotic FV (Leiden) and FII c.20210G>A mutations in Dagestani patients with obstructive hypertrophic cardiomyopathy (Radzhabova G., Motreva A., Kalmykova O., Dzemeshkevich S.L., Zaklyazminskaya E.V.)

09:45 – 10:00
Association of extrahepatic portal vein obstruction with hemostatic genes polymorphisms (Ibragimova Sh., Nadinskaya M.)

10:00 – 10:15
Carrying of pathological polymorphisms of folate cycle enzymes and hyperhomocysteinemia in clinical implementation of thromboses in neonates (Kuznetsov N., Abolina T., Filippova O.)

10:15 – 10:30
Gene polymorphisms of susceptibility to thrombophilia and folate metabolism in patients with pulmonary embolism (Ponasenko A., Tsepokina A., Trishkina N.)

BLUE 4+5


Scientific Session 29
Open issues in thrombosis and hemostasis
Chairs: Sturov V.G., Kuznik B.I.

09:00 – 09:15
The prevalence of genes polymorphism associated with thrombophilia in female residents of the Kaliningrad Region (Sturov V., Shostak D., Pashov A.)

09:15 – 09:30
Study of coagulation hemostasis in women with stable angina undergoing coronary artery bypass surgery (Fayl I., Bekmurzinova Z., Morova N.)

09:30 – 09:45
Thromboprophylaxis after complex congenital heart defects repair in children: acetylsalicylic acid or warfarin? (Kupryashov A., Gushin D., Samuilova D., Zelenikin M.)

09:45 – 10:00
Effectiveness of ozone therapy in patients with atherosclerosis of lower limb arteries and diabetes mellitus after microcirculation research (Ryapolova O., Bogach E., Aznaurova O.)

10:00 – 10:15
Assessment of coagulopathy and endothelial injury after traumatic brain injury during therapy with cytoflavin (Shumilova A., Deryugina A., Boyarinov G.)

10:15 – 10:30
The role of thrombotic risk factors in anemia correction in pregnant women (Buzyan L.)
GREEN 10


08:30 – 18:00
Educational Seminar in PBM: Focus on Perioperative Bleeding Management
Donau University Krems
Donau University Krems with Russian National Association on Thrombosis and Hemostasis (rus/eng; with synchr.translation)

Opening (Christian Fisher, Austria)

Physiology of blood coagulation and pathophysiology of acute coagulopathy (E.V.Roitman, Russia)

DIC (Catherine Scarlatescu, Romania)

Hemostatic agents (plasma, platelet concentrate) (E.B.Zhiburt, Russia)

Management of the system of hemostasis in pediatric surgery (Vyacheslav Savan, France)

Discussion (E.B.Zhiburt, all participants)

GREEN 8


09:00 – 18:00
One-Day Educational Seminar (rus).

Organized by National Scientific Society for Inflammation
«Russian Antithrombotic Forum»
Part 1

Chairs: Bouryachkovskaya L.I., Lomakin N.V.

09:00 – 10:00
Registration of participants

10:00 – 10:10
Opening (Roitman E.V.)

10:10 – 10:40
Antithrombotic therapy. What is new in our hands in the fall of 2018? (Buryachkovskaya L.I.)

10:40 – 11:10
Comparative effectiveness of the original and reproduced buffer forms of acetylsalicylic acid (Buryachkovskaya L.I.)

11:10 – 11:40
Antithrombotic therapy in coronary cardiology. Clinical recommendations and reality (Lomakin N.V.)

11:10 – 12:00
Coffee break

12:00 - 12:30
Antithrombotic therapy in angioneurology - beyond clinical guidelines (Shirokov E.A.)

12:30 - 13:00
Pulmonary embolism: modern approaches of supervision (Obrezan A.G.)

13:00 - 13:30
Antithrombotic therapy in patients with critical ischemia of lower limbs and diabetic foot syndrome (Eroshenko A.V.)

13:40
Closing, issuing certificates
10:30 – 11:00
Coffee break
11:00 – 12:30 Scientific Session 30
Hypercoagulation and Biomarkers, Assays for Hypercoagulability (rus/eng)
Chairs: Berkovsky A.L., Presnyakova M.V.

11:00 – 11:20
DOAC’s monitoring (Berkovsky A.L.)

11:20 – 11:35
Evaluation of platelet function using low angle light scattering: characterization of reproducibility, sensitivity and analytical variables (Svidelskaya G., Ignatova A., Mindukshev I., Gambaryan S., Panteleev M.)

11:35 – 11:50
Experience of thromboelastography application in the burned patients (Presnyakova M., Kuznetsova V., Kostina O.)

11:50 – 12:05
Thromboelastometry in women during pregnancy (Dashkevich E.)

12:05 – 12:20 New method of multimer analysis of von Willebrand factor in von Willebrand disease diagnostics: the experience of use (Poletaev A., Seregina E., Zharkov P., Karamyan N., Plyasunova S.)

12:20 – 12:30
Thrombodynamics potential for monitoring of anticoagulation (Balandina A., Koltsova E., Serebriyskiy I., Ataullakhanov F.)

NATH General Assembly


Chair: Roitman E.V.

11:00 – 11:10
Experience of the city hemostasis pathology department in Chelyabinsk for 13 years (Vereina N.K.)

11:10 – 11:20
Experience of the antithrombotic cabinets system in the Arkhangelsk region - focus on treatment safety and effectiveness (Vorobyova N.A.)

11:20 – 11:30
30 years of mobile hemostasis brigade in Ekaterinburg (Brazhnikov A.Yu.).

11:30 – 11:40
Prospects of the development of the centralized monitoring system of international normalized ratio (Khruslov M.)

11:40 – 11:50
Optimization of correction of hemostasis disturbances in obstetric bleedings on the experience of reanimation and transfusiological mobile team with hemostasis laboratory (Kubiddinov A., Saidov Ju., Odinaev A.)

11:50 – 12:30
About the work of the National Association for Thrombosis and Hemostasis (Roitman E.V.)
Scientific Session 31
Microcirculation and its importance in clinical trials
Chairs: Vlasov T.D., Krupatkin A.I., Petrishchev N.N.

11:00 – 11:15
The oscillatory processes significance of the microcirculation in clinical diagnosis (Krupatkin A.I., Sidorov V.V., Dunaev A.V.)

11:15 – 11:30
Investigation of the microcirculation endothelium as the quality assessing method of type 2 diabetes mellitus (Vlasov T.D., Petrishchev N.N. Simanankova A.V.)

11:30 – 11:45
New methodological approaches to monitoring the state of patients with bronchial asthma based on evaluation of peripheral blood flow and reactivity of blood granulocytes (Tikhonova I.V., Kosyakova N.I., Tankanag A.V., Grinevich A.A., Guseva I.E., Chemeris N.K., Safronova V.G.)

11:45 – 12:00
Telemonitoring of capillary blood flow in the skin. New opportunities and prospects (Fedorovich A.A.)

12:00 – 12:10
The capabilities of high-frequency doppler ultrasonography in exercise tolerance evaluation (Skedina M.A., Kovaleva A.A.)

12:10 – 12:20
High-frequency ultrasound dopplerography helps in diagnostics of diabetes mellitus complications (Zelenina T., Salukchov V., Zemlyanoy A., Volkova E.)

12:20 – 12:30
Effectiveness of ozone therapy in patients with atherosclerosis of lower limb arteries and diabetes mellitus after microcirculation research (Ryapolova O., Bogach E., Aznaurova O.)



12:00 – 12:45
Lunch for participants
12:30 – 12:45
Short Break to walk
Break to walk
12:45 – 13:45 Plenary Session (joint)
Pathophysiology of DVT – new insights (Vavilova T.V.)
(rus/eng; with synchr.translation)
13:45 – 14:15 Closing Ceremony of Joint International Meeting «COITH-2018 together with 9th Russian Conference on Clinical Hemostasiology and Hemorheology
Young Investigator Award.
COITH-2018 Closing Remarks. Announcement the COITH-2020.
9th Russian CCH Closing Remarks.
Educational Seminar in PBM: Focus on Perioperative Bleeding Management
Donau University Krems
Donau University Krems with Russian National Association on Thrombosis and Hemostasis
(rus/eng; with synchr.translation)

Bleeding in obstetrics and operative gynecology (Kestitis Rimaitis, Lithuania)

Diagnostic tools and laboratory tests (Mikael Spannagl, Germany)

Practice «Point Of Care Testing» (I.M.Kolesnikova, Russia)

Bleeding in neurosurgery (A.Kulikov, Russia)

Massive hemorrhages and massive blood transfusion: the pros and cons (debates). For: Kestitis Rimaitis, Against: E.B.Zhiburt

Closure (E.V.Roitman, E.B.Zhiburt, Christian Fisher, all participants)
One-Day Educational Seminar (rus).

Organized by National Scientific Society for Inflammation
«Russian Antithrombotic Forum for pharmacists» Chairs: Bouryachkovskaya L.I., Lomakin N.V.

16:00 - 16:30
Registration of participants

16:30 - 16:40
Opening

16:40 - 17:10
Antithrombotic agents are a therapy that saves lives. What you need to know the pharmacist and the first-in-command in everyday work (Lomakin N.V.)

17:10 - 17:20
Discussion

17:20 - 17:40
Coffee break

17:40 - 18:10
Antithrombotic therapy - how to understand the abundance of drugs and make the right choice (Buryachkovskaya L.I.)

18:10 - 18:20
Discussion

18:20
Closing, issuing certificates
Approx. starting from 15:00
Social Program (optional)